#3914 TRAJECTORY OF ANTHROPOMETRIC INDICATOR AND CLINICAL EVENTS AMONG PATIENTS ON HEMODIALYSIS

Abstract Background and Aims Low values for anthropometric indicators are risk factors adverse clinical outcomes among patients on hemodialysis (HD). Anthropometric parameters time-dependent; thus, reliance only baseline measurements may not sufficiently capture important patient outcomes. Nonetheless, little is known about the associations between trajectory of prognosis. We examined a one-year change in hospitalization mortality rates undergoing HD. Method This retrospective study collected data from outpatients HD at two dialysis facilities April 2018 March 2022. The five were evaluated, including body mass index (BMI), mid-upper arm circumference (MUAC), mid-arm muscle (MAMC), triceps skinfold (TSF), calf (CC). defined which was date first measurement assessments. Thereafter, we evaluated their trajectories over one year. Change 1-year calculated by subtracting value second assessment value. Patients divided into 2 groups according to indicators: no decline (≥0) (<0). all-cause death number duration hospitalizations. Death hospitalizations determined using facilities’ records. Negative binomial regressions used examine changes Results included 283 (mean age, 67.3 years; 60.4% males). During follow-up period (median, 2.7 years), 30 deaths 200 occurred. When considering as continuous variables, increasing BMI per 1 standard deviation (incident rate ratio [IRR]: 0.87; 95% confidence interval [CI]: 0.85–0.90), MUAC (IRR: 0.94; CI: 0.88–0.99), TSF 0.92; 0.84–0.99), MAMC 0.99; 0.98–0.99) associated with lower regardless any point time. However, CC events 0.83–1.07). Similarly, when considered categorical models, group 1.36, 1.30–1.43), 1.14, 1.02–1.28), 1.27, 1.05–1.53), 1.11, 1.03–1.19) had higher outcome than group. A significant association detected 0.93, 0.84–1.03) (Table 1). Conclusion observed that decreasing BMI, MUAC, TSF, time independently events. Routinely assessing these simple measures practice be useful management strategy prognostic stratification